Background: Nowadays, universities are not only the place for producing knowledge, but also they must take steps to adopt global standards in order to play their role in meeting social needs. This research was conducted with the aim of investigating the impact of globalization of university education on entrepreneurship and knowledge-based companies and the provision of the model. Methods: The present study is a mixed method type with two qualitative and quantitative phases. In the qualitative phase of the research, six experts and professionals related to the research topic were selected by snowball sampling method and interviewed. The obtained results were analyzed using Strauss and Corbin's three-step coding method, and the related model was designed. In the quantitative phase, a researcher-made questionnaire in former phase was provided for 384 students of the universities of Medical Sciences of Mashhad, and Azad university of Mashhad, selected by stratified random sampling. Descriptive and inferential statistics and SPSS-19 and Smart PLS-3 software were used to analyze the data. Results: According to the research findings, 293 participants were men and almost half of them had a bachelor's degree. Also, the significance level for the relationship between the globalization of university educations and entrepreneurship, the correlation between the university education globalization on the development of Knowledge-Based companies and, finally the relationship between entrepreneurship and the development of Knowledge-Based companies were less than 0.05. Conclusion: Regarding the role of Knowledge-Based companies in the economic and scientific development of countries and the impact of universities on supporting these companies, it is suggested that universities, by approximating themselves to the global criteria, play their role in advancing this route.
