Background and Objective: The purpose of this study was to evaluate the efficacy of metacognition therapy on improving the generic men sexual functions. Metacognition is "cognition about cognition", "thinking about thinking", "knowing about knowing", becoming "aware of one's awareness" and higher-order thinking skills. The term comes from the root word meta, meaning "beyond". Method: This study was conducted in a semi-experimental and pre-test-post-test design with control group. The community of this research was from men living in Tehran who had been at least two years of their last permanent marriage and between the ages of 20 and 45 and living in Iran. In this research, inferential statistics test (repeated measurement of mixed method and post hoc test, least significant difference) were analyzed. spss 23 software was used to analyze the data. Measurement tool in this research was a male sexual function questionnaire. Results: The findings of the study showed that the subjects in the metacognition group had an increase of 18.2% in the post-test and 18.8% in comparison with the pre-test in the generic sexual function. The result of the study was that the intervention by metacognition therapy method had an impact on generic men sexual function. Conclusion: The results of this study indicate that interventions using metacognition therapy are effective in improving generic men sexual functions, and it is possible to emphasize the need for more attention to cognitive interventions, including the approach of metacognition therapy in the field of sexual issues.