The purpose of this study is to investigate the impact of factors related to the job, which are Job Demand, Job Control, and Social Support, on lecturer performance in Hanoi. Facing increasing competition, job performance is the main concern of all the organizations. The performance of each employee and the collaboration among employees while they are working are the main components of organizational performance. This research applies the Job Demand- Control and Social Support model to investigate the impact of factors that influence the performance of employees who are lecturers working in Universities in Vietnam. The questionnaire was sent to the lecturers who are working in Hanoi, Vietnam, via the online system, and there were 153 lecturers who completed the form. The data collected was analyzed by applying AMOS and SPSS, and the hypothesis was supported by data analysis. The results indicated that Job Demand has a negative impact on the lecturer's performance, while Job Control and Social Support have a significant influence on the lecturer's performance in Hanoi, Vietnam. The results also figure out the moderate impact of Job Control and Social Support on the impact of Job Demand on the Lecturer's Performance. The results of this study also suggest solutions for university managers to improve lecturer performance.