Scientific interactions and cooperation are among the main components of science production. The interaction and communication among the faculty members are considered as one of the most important areas of communication in higher education. Thus, the level of interactions, communication and collaborative activities plays major role in the professional development of faculty members. The main objective of this research is to answer the main question of what are the main barriers to professional interaction and scientific cooperation among faculty members. This research is descriptive-analytical in terms of nature. It uses content analysis method. To achieve this goal, an open-ended question was developed. The purposeful sampling method was used in this research and a total of 67 faculty members participated in this research. Based on the research results, the barriers of professional interactions of faculty members were identified and categorized in 9 categories of cultural, individual characteristics, legal / regulatory, financial, political, attitudinal, motivational, planning and policy-making, and infrastructure categories. Finally, the results showed that sub-category of lack of budget and non-allocation of adequate budget is the first priority of barriers. In addition, the sub -categories of lack of group and collective work culture, individual and personality characteristics of people, inhibitory rules of university in collaborative and joint work (administrative bureaucracy), ideological dependence to ruling parties, lack of support and encouragement of faculty members in scientific cooperation, inadequate design of university structures for performing educational and research activities ranked second among the barriers identified.
