According to 1WHO estimates, 800,000 people die of cardiovascular, respiratory and respiratory diseases and airborne lung cancer everywhere in the world, with nearly 150,000 deaths occurring in South Asia. The results of studies on the short-term and long-term effects of hospitalization, referral to the doctor, the number of cases of a specific illness, death and number of years lost in life (YOLL) are reported. The 2Air Q2.2.3 computer model was used to evaluate the effects of exposure to PM10 contaminants on human health in Tabriz metropolitan area. Major sources of emissions are due to human interference with suspended particles of road traffic (10-25%), constant combustion (40- 55%) and industrial processes (15-30%). Materials and methods: In this study, The needs of the Environmental Organization and the Meteorological Organization of Tabriz were gathered. In the next step, the data was processed by Excel software by performing temperature and pressure correction steps, programming, processing (average) and filtering. At the final stage, data processed by Excel was given to the Air Q model. This model is a reliable and reliable tool for estimating the short-term effects of air pollutants by the World Health Organization. The results show that the cases of cardiovascular and respiratory diseases related to atmospheric pollutants during the 10 year period with 4093 and 3353 people, respectively, were %33.10 and %40.7respectively.