Information technology is playing an important role in Pakistan. Electronic human resource management (E-HRM) is a new phenomenon to create new opportunities and cost-effective benefits in any organization. The purpose of this study was to trace out the difference between the perceptions of university administrators from public and private sectors about the use of e-HRM practices. For this purpose, a questionnaire (e-HRMPQ) based on fifteen items was developed on Likert five-point scale. The validity and reliability were found through pilot study. This research was based on survey quantitative nature research design. After maintaining target and accessible population, multi stage sampling technique was used to select representative sample. The data was gathered from ‘387’ administrators (public and private) through postal services and personal visits. The objectives of the study were fulfilled through the analysis of data with the help of SPSS-21 software. The administrators from private sector universities have statistically significant differences over the administrators from public sector universities about the use of e-HRM practices. The Higher Education Commission (HEC), Pakistan should take exemplary initiatives in public sector universities to meet future challenges.