Psychological factors, such as personality and behavioral characteristics, are the effective factors in hypertension. This research investigates the relationship between brain-behavioral systems and sensory processing sensitivity with hostility in patients with hypertension. 150 male and female hypertensive patients (30 to 60 years old) referring to Tabriz Madani Hospital were selected by sampling at convenience. Data were collected by the questionnaires of Redford-Williams hostility, Highly Sensitive Person scale and Carver-White's approach/inhibition scale. Pearson's correlation test and multiple linear regression with SPSS software were used for data analysis. As the results showed, there is a significant inverse relationship between behavioral activation system and hostility in patients with hypertension (P=0.001). There is a significant positive relationship between behavioral inhibition system and high sensory processing sensitivity with hostility in patients with hypertension (P=0.001). The variables of the inhibitory system, the behavioral activating system and the high sensory processing sensitivity explain 44% of the variance of the hostility in patients with hypertension. The high sensory processing sensitivity has a greatest effect on the hostility in patients with hypertension.
